2008 Papers published using GeneChem techniques and service: ↑

1.Wang L, Zhou GB, Liu P, Song JH, Liang Y, Yan XJ, Xu F, Wang BS, Mao JH, Shen ZX, Chen SJ, and Chen Z (2008) Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia.

Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4826-31.          PDF

2.Zheng J, Shen WH, Lu TJ, Zhou Y, Chen Q, Wang Z, Xiang T, Zhu YC, Zhang C, Duan S, Xiong ZQ . (2008) Clathrin-dependent endocytosis is required for TrkB-dependent Akt-mediated neuronal protection and dendritic growth.

J Biol Chem. 2008 May 9;283(19):13280-8.          PDF

3.Zhang H, Feng W, Liao W, Ma X, Han Q, Zhang Y. (2008) The gp130/STAT3 signaling pathway mediates beta-adrenergic receptor-induced atrial natriuretic factor expression in cardiomyocytes.

FEBS J. 2008 Jul; 275(14):3590-7.          PDF

4.Sun Y, Liu M, Yang B, Li B, Lu J. (2008) Role of siRNA silencing of MMP-2 gene on invasion and growth of laryngeal squamous cell carcinoma.

Life Eur Arch Otorhinolaryngol. 2008 Apr 25.          PDF

5. Xu J, Qu J, Cao L, Sai Y, Chen C, He L, Yu L. (2008) Mesenchymal stem cell-based angiopoietin-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice.

J J Pathol. 2008 Mar;214(4):472-81.           PDF

6.Li ZHANG, Hou-jia LIU, Tie-jun LI, Yang YANG, Xian-ling GUO, Meng-chao WU, Yao-cheng RUI, Li-xin WEI. (2008)Lentiviral vector-mediated siRNA knockdown of SR-PSOX inhibits foam cell formation in vitro

Acta Pharmacologica Sinica 2008 July; 29 (7): 847-852          PDF

7.Wu LP, Wang X, Li L, Zhao Y, Lu S, Yu Y, Zhou W, Liu X, Yang J, Zheng Z, Zhang H, Feng J, Yang Y, Wang H, Zhu WG . (2008) Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.

Cell Mol Cell Biol. 2008 May;28(10):3219-35.          PDF

8.Liu N, Zhang J, Zhang J, Liu S, Liu Y, Zheng D.. (2008) Erbin-regulated Sensitivity of MCF-7 Breast Cancer Cells to TRAIL via ErbB2/AKT/NF-{kappa}B Pathway.

Mol J Biochem. 2008 Jun;143(6):793-801.          PDF

9.Shen C, Chen Y, Liu H, Zhang K, Zhang T, Lin A, Jing N. (2008) Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase.

Cell J Biol Chem. 2008 Jun 20;283(25):17721-30.          PDF

10.Wang C, Li N, Liu X, Zheng Y, Cao X.. (2008)  A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization.

J Biol Chem. 2008 Apr 25;283(17):11565-74.          PDF

11.Sun Q, Zhang Y, Yang G, Chen X, Zhang Y, Cao G, Wang J, Sun Y, Zhang P, Fan M, Shao N, Yang X. (2008) Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation.

Acta Nucleic Acids Res. 2008 May;36(8):2690-9.           PDF

12.Xiang J, Gu X, Qian S, Chen Z. (2008) Graded function of CD80 and CD86 in initiation of T-cell immune response and cardiac allograft survival.

Mol Transpl Int. 2008 Feb;21(2):163-8.          

13.Yang S, Liu X, Yin Y, Fukuda MN, Zhou J. (2008)Tastin is required for bipolar spindle assembly and centrosome integrity during mitosis.

Acta FASEB J. 2008 Jun;22(6):1960-72.          PDF

14.Li C, Liu Q, Li N, Chen W, Wang L, Wang Y, Yu Y,and Cao X. (2008)  EAPF/Phafin-2, a novel endoplasmic reticulum-associated protein, facilitates TNF-alpha-triggered cellular apoptosis through endoplasmic reticulum-mitochondrial apoptotic pathway.

J Mol Med. 2008 Apr;86(4):471-84.          PDF

15.Chen S, Zhang M, Ma H, Saiyin H, Shen S, Xi J, Wan B and Yu L. (2008) Oligo-microarray analysis reveals the role of cyclophilin A in drug resistance.

Acta Cancer Chemother Pharmacol. 2008 Mar;61(3):459-69.           PDF

16.Chai G, Li L, Zhou W, Wu L, Zhao Y, Wang D, Lu S, Yu Y, Wang H, McNutt MA, Hu YG, Chen Y, Yang Y, Wu X, Otterson GA and Zhu WG. (2008) HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.

Mol PLoS ONE. 2008 Jun 18;3(6):e2445.           PDF

17.Chen SW, Chen YX, Zhang XR, Qian H, Chen WZ, Xie WF. (2008) Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats.

Acta Gene Ther. 2008 May 29.          PDF

18.Chen SW, Zhang XR, Wang CZ, Chen WZ, Xie WF, Chen YX. (2008)  RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats.

Liver Int. 2008 May 6.          PDF

19.Liang Da-ning, Gao Jian-hua and Lu Feng. (2008) Effects of specific small interfering RNA-mediated cyclinD1 gene silencing on the growth of human keloid fibroblasts

Acta J Clin Rehabil Tissue Eng Res No.310 Vol.12 No.2 January 8.2008          

20.Zhang GY, Yi CG, Li X, Zheng Y, Niu ZG, Xia W, Meng Z, Meng CY and Guo SZ. (2008) Inhibition of vascular endothelial growth factor expression in keloid fibroblasts by vector-mediated vascular endothelial growth factor shRNA: a therapeutic potential strategy for keloid.

Mol Arch Dermatol Res. 2008 Apr;300(4):177-84.           PDF

2007 Papers published using GeneChem techniques and service: ↑

1.C Ma, J Zhang, LK Durrin, J Lv, D Zhu, X Han and Y Sun (2007) The BCL2 major breakpoint region (mbr) regulates gene expression.

Oncogene. 2007 Apr 19;26(18):2649-57.          PDF

2.Wang L, Yu C, Lu Y, He P, Guo J, Zhang C, Song Q, Ma D, Shi T, Chen Y. (2007) TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis.

Apoptosis. 2007 Aug;12(8):1489-502.          PDF

3.Yu J, Liu J, Sun Y, Liu Y, Zhu T, Xie Y, Zha J, Ding G. (2007) Mechanisms of the Adipogenic Effect of 11{beta}-hydroxysteroid Dehydrogenase Type 1: Relationship with the Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor {gamma} Pathway.

Endocrinology. 2007 Apr 12;          PDF

4.Ma X, Wang X, Gao X, Wang L, Lu Y, Gao P, Deng W, Yu P, Ma J, Guo J, Cheng H, Zhang C, Shi T, Ma D. (2007) Identification of five human novel genes associated with cell proliferation by cell-based screening from an expressed cDNA ORF library.

Life Sci. 2007 Sep 15;81(14):1141-51.          PDF

5.Jin C, Wang Y, Han W, Zhang Y, He Q, Li D, Yin C, Tian L, Liu D, Song Q, Ma D. (2007) CMTM8 induces caspase-dependent and -independent apoptosis through a mitochondria-mediated pathway.

J Cell Physiol. 2007 Apr;211(1):112-20.           PDF

6.Wang J, Li Y, Zhang M, Liu Z, Wu C, Yuan H, Li YY, Zhao X, Lu H. (2007) A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbbeta and removes Rev-erbbeta-induced inhibition of apoCIII transcription.

FEBS J. 2007 Oct;274(20):5370-81.          PDF

7.Fang L, Wang Y, Du D, Yang G, Kwok TT, Kong SK, Chen B, Chen DJ, Chen Z. (2007) Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.

Cell Res. 2007 Jun;17(6):572-574.          PDF

8.Ma X, Zhao H, Shan J, Long F, Chen Y, Chen Y, Zhang Y, Han X, Ma D. (2007) PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.

Mol Biol Cell. 2007 Jun;18(6):1965-78.          PDF

9.Meng YG, Han WD, Zhao YL, Huang K, Si YL, Wu ZQ, Mu YM. (2007) Induction of the LRP16 gene by estrogen promotes the invasive growth of Ishikawa human endometrial cancer cells through the downregulation of E-cadherin.

Cell Res. 2007 Oct;17(10):869-80.          PDF

10.Yu YG, Tang FG, Pan J, Gu XF. (2007)  Effects of phenylalanine and its metabolites on cytoplasmic free calcium in cortical neurons.

Neurochem Res. 2007 Aug;32(8):1292-301.          PDF

11.Liu Y, Sun Y, Zhu T, Xie Y, Yu J, Sun WL, Ding GX, Hu G. (2007) 11 beta-hydroxysteroid dehydrogenase type 1 promotes differentiation of 3T3-L1 preadipocyte.

Acta Pharmacol Sin. 2007 Aug;28(8):1198-204.           PDF

12.Liang J, Ke G, You W, Peng Z, Lan J, Kalesse M, Tartakoff AM, Kaplan F, Tao T. (2007) Interaction between importin 13 and myopodin suggests a nuclear import pathway for myopodin.

Mol Cell Biochem. 2008 Jan;307(1-2):93-100.           PDF

13.Jin W, Wu J, Zhuang Z, Li J, Fei F, Di G, Chen Y, Yao M, Shao Z. (2007) Gene expression profiling in apoptotic k562 cells treated by homoharringtonine.

Acta Biochim Biophys Sin (Shanghai). 2007 Dec;39(12):982-91.          PDF

14.Jianbin Xiang, Xiaodong Gu, Shiguang Qian and Zongyou Chen. (2007)  Graded function of CD80 and CD86 in initiation of T-cell immune response and cardiac allograft survival

Transplant International. 2007; 21(2008):163-168.          PDF

15.Zhifeng Xiao, Yaxian Kong, Shufa Yang, Meiyu Li, Jinhua Wen and Lingsong Li. (2007) Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation

Acta Cell Research 2007 (17):73-79.           PDF

16.Shan Ke, Xue-Hua Chen, Hao Li, Jian-Fang Li, Qin-Long Gu, Bing-Ya Liu and Zheng-Gang Zhu. (2007) Silencing invariant chain of DCs enhances Th1 response using small interfering RNA

Mol Cell Biology International 2007 (31):663-671.           PDF

1.Man-Li Luo, Xiao-Ming Shen, Yu Zhang, Fang Wei, Xin Xu, Yan Cai, Xun Zhang,Yun-Tian Sun, Qi-Min Zhan, Min Wu, and Ming-Rong Wang (2006) Amplification and Overexpression of CTTN (EMS1) Contribute to the Metastasis of Esophageal Squamous Cell Carcinoma by Promoting Cell Migration and Anoikis Resistance

Cancer Res. 66: (24)          PDF

2.Yang Zhou, Hao Wu, Shuai Li, Qian Chen, Xue-Wen Cheng, Jing Zheng, Hiroshi Takemori, and Zhi-Qi Xiong (2006) Requirement of TORC1 for Late-Phase Long-Term Potentiation in the Hippocampus

PLoS ONE Issue 1:e16          PDF

3.Yanmei Tao, Dong Yan, Qiaoyun Yang, Rui Zeng, and Yizheng Wang (2006) Low K+ Promotes NF- B/DNA Binding in Neuronal Apoptosis Induced by K+ Loss.

Mol. Cell Biol. 26: 1038-1050          PDF

4.Jin-zhong Chen, Chao-neng Ji, Guan-lan Xu,Rong-yan Pang, Ji-hua Yao, Huan-zhang Zhu,Jing-lun Xue, and William Jia (2006) DAXX interacts with phage ΦC31 integrase and inhibits recombination.

Nucleic Acids Res. 34(21): 6298–6304.          PDF

5.L. N. Chen, Y. Wang, D. L. Ma and Y. Y. Chen (2006) Short interfering RNA against the PDCD5 attenuates cell apoptosis and caspase-3 activity induced by Bax overexpression.

Apoptosis 11: 101–111          PDF

6.Guangming Li,Qing Xie,Yi Shi,Dingguo Li,Mingjun Zhang,Shan Jiang,Huijuan Zhou,Hanming Lu,Youxin Jin (2006)Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats

J Gene Med 8: 889–900.          PDF

7.Yan Zhang,Mei-Yu Hu,Wei-Zhong Wu,Zhi-Jun Wang,Kang Zhou ,Xi-Liang Zha, and Kang-Da Liu (2006)The membrane-cytoskeleton organizer ezrin is necessary for hepatocellular carcinoma cell growth and invasiveness

J Cancer Res Clin Oncol 132:685–697          PDF

8.Guangming Li, Qing Xie, Yi Shi, Dingguo Li, Mingjun Zhang, Shan Jiang, Huijuan Zhou, Hanming Lu, Youxin Jin (2006) Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats.

The Journal of Gene Medicine  8(7):889-900          PDF

9.X. Gu, J. Xiang, Y. Yao and Z. Chen (2006) Effects of RNA Interference on CD80 and CD86 Expression in Bone Marrow-derived Murine Dendritic Cells.

Scandinavian Journal of Immunology 64(6):588-98          PDF

10.Yong Zhang, Wei Zhu, Yong-Gang Wang, Xiu-Jie Liu, Li Jiao, Xuan Liu, Zhao-Huan Zhang, Chang-Lin Lu and Cheng He (2006) Interaction of SH2-Bß with RET is involved in signaling of GDNF-induced neurite outgrowth.

Journal of Cell Science 119:1666-1676           PDF

11.Xue-Hua Chen, Bin Lan, Ying Qu, Xiao-Qing Zhang, Qu Cai, Bing-Ya Liu, and Zheng-Gang Zhu (2006) Inhibitory effect of Polo-like kinase 1 depletion on mitosis and apoptosis of gastric cancer cells.

World J Gastroenterol.12(1): 29-35          PDF

12.Ke Shan and Bingya Liu (2007) Optimization of Electroporation Parameters for Transfection of Plasmid DNA into Murine Bone Marrow-Derived Dendritic Cell

Journal of Shanghai Second Medical University, 2006 (2:)          PDF

13.Yanyong Kang, Fengcai Wang, Jing Feng, Dongling Yang, Xu Yang, and Xiyun Yan (2006) Knockdown of CD146 reduces the migration and proliferation of human endothelial cells

Cell Research .2006(16): 313-318          PDF

1.Jun Gao, Bo Duan, De-Guang Wang, Xiao-Hong Deng, Guang-Yi Zhang, Lin Xu and Tian-Le Xu (2005) Coupling between NMDA Receptor and Acid-Sensing Ion Channel Contributes to Ischemic Neuronal Death.

Neuron 48: 635–646          PDF

2.Jiuhong Kang, Yufeng Shi, Bin Xiang, Bin Qu, Wenjuan Su, Min Zhu, Min Zhang, Guobin Bao, Feifei Wang, Xiaoqing Zhang, Rongxi Yang, Fengjuan Fan, Xiaoqing Chen, Gang Pei and Lan Ma (2005)A Nuclear Function of b-Arrestin1 in GPCR Signaling: Regulation of Histone Acetylation and Gene Transcription.

Cell 123: 833–847.          PDF

3.Li Y, Jia YC, Cui K, Li N, Zheng ZY, Wang YZ, and Yuan XB. (2005) Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor.

Nature 434: 894-898.           PDF

4.Wang T, Xia D, Li N, Wang C, Chen T, Wan T, Chen G, and Cao X. (2005) Bone marrow stromal cell-derived growth inhibitor, BDGI, inhibits growth and migration of breast cancer cells via induction of cell cycle arrest and apoptosis.

J Biol Chem. 280(6):4374-82.          PDF

5.Caining Jin, Peiguo Ding, Ying Wang, and Dalong Ma (2005) Regulation of EGF receptor signaling by the MARVEL domain-containing protein CKLFSF8.